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Table 2 Plasma levels of markers of inflammation (hsCRP), microbial translocation (LPS, sCD14, and LBP) and gastrointestinal damage (I-FABP) in ME/CFS and healthy individuals

From: Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome

Analytes Control ME/CFS
hsCRP (mg/L)
n 34 46
 Median 1.21 1.38
 Quartiles 0.38–2.69 0.70–2.71
 Range 0.27–5.09 0.23–19.3
LPS (pg/mL)
n 39 49
 Median 74.74 119.43
 Quartiles 54.34–99.54 66.21–144.41
 Range 32.21–187.32 34.32–279.30
I-FABP (pg/mL)
n 33 44
 Median 234.40 255.85
 Quartiles 159.75–412.90 171.275–450.70
 Range 14–1067.9 23.2–909.9
sCD14 (ug/mL)
n 39 49
 Median 1.36 1.97
 Quartiles 1.09–1.67 1.71–2.32
 Range 0.62–2.42 0.95–3.02
LBP (ug/mL)
n 37 49
 Median 12.32 17.68
 Quartiles 10.22–13.73 13.04–22.56
 Range 8.65–18.76 7.06–34.52