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Fig. 4 | Microbiome

Fig. 4

From: Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production

Fig. 4

Model for the indirect influence of Bacteroides or Akkermansia on butyrate production. Incomplete degradation of mucins in microbial communities dominated by Bacteroides leads to increased levels of sulfate. In contrast, Akkermansia can fully degrade mucins and use sulfate in an assimilatory manner. Concerning hydrogenotrophs, acetogens might outperform sulfate-reducing bacteria in microbial communities with increased Akkermansia abundances. Furthermore, acetate production by acetogens enhances butyrate production via co-fermentation of acetate (but-pathway)

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