Table 2 Detection of C. difficile and its toxins in four asymptomatically colonized and four CDI patients
Patient ID | Sample type | Toxigenic culturea | Enzyme immunoassayc | WMGS sequencing | ||
|---|---|---|---|---|---|---|
Culture | Toxinb | No. of reads | Relative abundance of C. difficile (%) | |||
Asymptomatically colonized | ||||||
30 | Rectal swab | Positive | Negative | ND | 8,487,324 | 0.000 |
63 | Rectal swab | Positive | Positive | ND | 10,366,360 | 0.000 |
87 | Rectal swab | Positive | Negative | ND | 4,489,956 | 0.363 |
99 | Stool | Positive | Positive | ND | 14,952,432 | 0.064 |
CDI | ||||||
35 | Stoold | Negative | ND | Positive | 5,926,081 | 0.000 |
36 | Stoold | Positive | Positive | ND | 7,068,998 | 0.017 |
55 | Stool | Positive | Positive | Positive | 9,950,687 | 0.003 |
98 | Stool | Negative | ND | Positive | 4,337,018 | 0.000 |