Table 1 Pathways enriched in transcripts displaying large (>fivefold) differences in relative expression between mouse cecal wall and cecal flush samples
| Â | Â | Fold change in expression | Differentially expressed genes | Matched ECs/total ECs in pathway | |||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Â | Genes up-regulated in cecal wall | Genes up-regulated in cecal flush | ||||||
Pathway | p value | 5–10 | 10–20 | >20 | 5–10 | 10–20 | >20 | ||
Glycolysis/gluconeogenesis | 9.35E-07 | 14 | 5 | 3 | 5 | 4 | 1 | 32 | 11/45 |
Methane metabolism | 6.44E-05 | 10 | 5 | 3 | 4 | 5 | 2 | 29 | 11/68 |
Carbon fixation in photosynthetic organisms | 1.00E-04 | 8 | 1 | 2 | 4 | 0 | 0 | 15 | 5/25 |
One carbon pool by folate | 2.88E-04 | 4 | 3 | 0 | 1 | 2 | 0 | 10 | 6/24 |
Starch and sucrose metabolism | 4.59E-04 | 5 | 4 | 2 | 3 | 3 | 0 | 17 | 10/71 |
Alanine, aspartate and glutamate metabolism | 1.43E-03 | 9 | 1 | 0 | 0 | 1 | 0 | 11 | 7/43 |
Citrate cycle (TCA cycle) | 1.52E-03 | 4 | 0 | 2 | 2 | 1 | 0 | 9 | 5/22 |
Pyruvate metabolism | 3.08E-03 | 7 | 0 | 2 | 1 | 1 | 1 | 12 | 8/62 |
Amino sugar and nucleotide sugar metabolism | 6.63E-03 | 5 | 3 | 1 | 1 | 3 | 2 | 15 | 9/85 |
Oxidative phosphorylation | 1.10E-02 | 2 | 3 | 1 | 0 | 3 | 0 | 9 | 3/12 |
Purine metabolism | 3.08E-03 | 10 | 0 | 0 | 2 | 0 | 2 | 14 | 9/100 |
Propanoate metabolism | 3.37E-02 | 3 | 0 | 0 | 0 | 1 | 1 | 5 | 5/45 |
Valine, leucine and isoleucine biosynthesis | 3.40E-02 | 1 | 1 | 0 | 0 | 1 | 2 | 5 | 3/18 |
Aminoacyl-tRNA biosynthesis | 3.85E-02 | 2 | 0 | 0 | 1 | 0 | 3 | 6 | 4/32 |
Histidine metabolism | 4.25E-02 | 1 | 3 | 0 | 1 | 0 | 0 | 5 | 4/33 |
Drug metabolism—other enzymes | 4.49E-02 | 3 | 0 | 0 | 0 | 0 | 0 | 3 | 3/20 |
Other glycan degradation | 4.88E-02 | 1 | 1 | 0 | 0 | 0 | 0 | 2 | 2/9 |