Fig. 1

Schematic overview of the classification model generation. Pink and green points represent individual kIBS and kHLT samples, respectively, distributed in the simulated T-vs-T_orthogonal PLS ordination space. Blue point represents an unknown sample that is classified by the PLS-DA models. M and C denote overall microbiota- and metabolite-based classification models, respectively; G is the group identifier; b _0…n are numerical parameters and m _1…n and c _1…p are values of specific microbes and metabolites, respectively. See statistical data analyses section for the definitions of Bayesian model terms and parameters