Protein relative abundance patterns associated with sucrose-induced dysbiosis are conserved across taxonomically diverse oral microcosm biofilm models of dental caries

Table 3 edgeR results for HOMINGS probes abundant in ≥5 samples: WS microcosms vs. Plaque

HOMINGS taxon probe^a	logFC^b	adjPValue^c	Abundance >1%^d
Streptococcus_Genus_probe	−2.99	1	9
Neisseria_Genus_probe	8.76	0.38	8
Rothia_Genus_probe	4.20	6.52E-03*	6
Granulicatella_adiacens_&_paradiacens	−2.89	1	6
Haemophilus_parainfluenzae	2.15	1	6
Rothia_aeria	6.30	1	6
Streptococcus_gordonii_&_sanguinis	−3.10	1	6
Veillonella_dispar	−2.68	1	6
Fusobacterium_Genus_probe	2.10	1	6
Veillonella_Genus_probe	−2.67	1	6
Corynebacterium_durum	8.51	<0.00E-163*	5
Lautropia_mirabilis	9.33	1.56E-09*	5
Abiotrophia_defectiva	4.93	5.36E-04*	5
Gemella_haemolysans	4.16	3.15E-03*	5
Rothia_dentocariosa	3.64	1	5

^aFormatted as per HOMINGS output
^bLog fold-change WS:P
^c p values adjusted using the Benjamini-Hochberg procedure, controlling the FDR at 5 %; an adjusted p value of 1 reflects rounding by Excel of values >0.999; asterisk indicates FDR ≤ 5 %
^dNumber of plaque samples in which reads for a probe were ≥1 % (as a percent of total reads)

ISSN: 2049-2618