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Fig. 2 | Microbiome

Fig. 2

From: Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis

Fig. 2

Infection with N. brasiliensis modulates the ileal microbiota in mice. Mice infected with N. brasiliensis were euthanized at day 11 post-inoculation and metagenomic DNA isolated from ileal tissue samples including luminal content and subjected to 16S rRNA gene short amplicon sequencing. a Microbial diversity calculated with the Shannon diversity index and compared with the Mann–Whitney test. b Qualitative (un-weighted UniFrac) and c quantitative (weighted UniFrac) phylogenetic distance calculations. d Taxonomic phyla and e families with differential abundance in N. brasiliensis-infected compared to uninfected mice as calculated with the non-parametric Fisher test as implemented in Metastats. Data shown in bar graphs are the mean ± s.e.m. *P < 0.05 versus vehicle (n = 10 for vehicle group and n = 9 for N. brasiliensis-infected group)

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