Fig. 2From: Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis Infection with N. brasiliensis modulates the ileal microbiota in mice. Mice infected with N. brasiliensis were euthanized at day 11 post-inoculation and metagenomic DNA isolated from ileal tissue samples including luminal content and subjected to 16S rRNA gene short amplicon sequencing. a Microbial diversity calculated with the Shannon diversity index and compared with the Mann–Whitney test. b Qualitative (un-weighted UniFrac) and c quantitative (weighted UniFrac) phylogenetic distance calculations. d Taxonomic phyla and e families with differential abundance in N. brasiliensis-infected compared to uninfected mice as calculated with the non-parametric Fisher test as implemented in Metastats. Data shown in bar graphs are the mean ± s.e.m. *P < 0.05 versus vehicle (n = 10 for vehicle group and n = 9 for N. brasiliensis-infected group)Back to article page