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Table 2 SCFA and metabolites with differential expression in fecal samples of 18 Malawian children fed with RS

From: The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children

 

Habitual diet

Habitual diet + RS

p value

SCFA (μmol/g)

 Total short-chain fatty acids

38.0 ± 8.6

35.9 ± 9.7

0.557

 Acetate

23.0 ± 6.4

17.8 ± 6.6

0.003*

 Propionate

6.5 ± 2.1

8.5 ± 3.0

0.007*

 Butyrate

8.5 ± 2.6

9.7 ± 4.1

0.306

 

Mean ratio

95 % CI

 

Metabolite

   

 3,4-Di-hydroxy-butanoate

4.3

[2.6, 5.9]

 

 β-Alanine

5.5

[1.7, 9.3]

 

 2-Hydroxy-butyrate

8.4

[3.6, 13.2]

 

 Malate

70

[1.9, 139]

 

 Citramalate

41

[15, 67]

 

 Phenylacetate

5.1

[2.0, 8.3]

 
  1. Values expressed as mean ± SD; P value determined by Wilcoxon Signed Ranks test. The metabolites are expressed as average of the ratio of concentration in stool after RS versus before RS administration for each child
  2. CI confidence interval
  3. *Significant difference p < 0.05