Unweighted UniFrac 3D PCoA illustrating changes in microbiota over 3 months. The panels represent microbial community changes over time in the (A) cat oral cavity, (B) cat nares, (C) dog oral cavity, (D) dog nares, (E) human inguinal crease/axillae, (F) human nares, and (G) human healing lesions. Each vector represents the microbial community of an individual at baseline and at 3 months, represented by the spheres. The sample number, n, is the total sample number from both visits. MID median intersample distances. The R values are obtained from Table 4; *p < 0.05.