TY - JOUR AU - Misic, Ana M. AU - Davis, Meghan F. AU - Tyldsley, Amanda S. AU - Hodkinson, Brendan P. AU - Tolomeo, Pam AU - Hu, Baofeng AU - Nachamkin, Irving AU - Lautenbach, Ebbing AU - Morris, Daniel O. AU - Grice, Elizabeth A. PY - 2015 DA - 2015/01/23 TI - The shared microbiota of humans and companion animals as evaluated from Staphylococcus carriage sites JO - Microbiome SP - 2 VL - 3 IS - 1 AB - Staphylococcus aureus and other coagulase-positive staphylococci (CPS) colonize skin and mucous membrane sites and can cause skin and soft tissue infections (SSTIs) in humans and animals. Factors modulating methicillin-resistant S. aureus (MRSA) colonization and infection in humans remain unclear, including the role of the greater microbial community and environmental factors such as contact with companion animals. In the context of a parent study evaluating the households of outpatients with community MRSA SSTI, the objectives of this study were 1) to characterize the microbiota that colonizes typical coagulase-positive Staphylococcus spp. carriage sites in humans and their companion pets, 2) to analyze associations between Staphylococcus infection and carriage and the composition and diversity of microbial communities, and 3) to analyze factors that influence sharing of microbiota between pets and humans. SN - 2049-2618 UR - https://doi.org/10.1186/s40168-014-0052-7 DO - 10.1186/s40168-014-0052-7 ID - Misic2015 ER -