Table 1 Metabolic pathways found to be enriched in VirMic

ko00240

Pyrimidine metabolism

4.058130678

10

165

K00525, K00526, K00762, K01493, K02323, K02335, K03006, K03465, K10807, K10808

ko03030

DNA replication

2.967323268

4

51

K02314, K02335, K03111, K10755

ko00230

Purine metabolism

2.475427099

10

251

K00525, K00526, K00860, K00939, K01768, K02323, K02335, K03006, K10807, K10808

ko00051

Fructose and mannose metabolism

2.337880458

5

77

K00971, K01623, K01711, K01809, K02377

ko00670

One carbon pool by folate

1.568059864

2

27

K00605, K03465

ko03430

Mismatch repair

1.346727877

2

45

K03111, K10755

ko00540

Lipopolysaccharide biosynthesis

1.215485245

2

34

K00979, K03111

ko00480

Glutathione metabolism

0.930033621

2

39

K10807, K10808

ko00710

Carbon fixation in photosynthetic organisms

0.866466913

2

36

K01623, K01808

ko00520

Amino sugar and nucleotide sugar metabolism

0.740996687

4

129

K00971, K01711, K01809, K02377

ko03420

Nucleotide excision repair

0.699379877

2

48

K02335, K10755

ko00680

Methane metabolism

0.679862658

4

224

K00124, K01079, K01623, K08350

ko03440

Homologous recombination

0.626567452

2

59

K02335, K03111

ko00030

Pentose phosphate pathway

0.547242261

2

57

K01623, K01808

ko00061

Fatty acid biosynthesis

0.533333333

1

30

K02371

ko00195

Photosynthesis

0.528989459

2

63

K02703, K02706

ko00770

Pantothenate and CoA biosynthesis

0.5

1

32

K00606

ko00630

Glyoxylate and dicarboxylate metabolism

0.425930951

2

76

K00124, K08350

ko04113

Meiosis - yeast

0.388260624

2

99

K01768, K02604

ko00260

Glycine, serine and threonine metabolism

0.351753529

2

85

K00605, K01079

ko03060

Protein export

0.256223722

1

39

K03217

ko00521

Streptomycin biosynthesis

0.175276585

1

18

K01710

ko04122

Sulfur relay system

0.163056569

1

21

K11179

ko00910

Nitrogen metabolism

0.162848544

2

117

K00459, K00605

ko04112

Cell cycle – Caulobacter

0.162846923

1

31

K02314

ko00071

Fatty acid metabolism

0.162080418

1

49

K06445

ko03070

Bacterial secretion system

0.135036827

1

74

K03217

ko00010

Glycolysis/Gluconeogenesis

0.133035339

1

91

K01623

ko00190

Oxidative phosphorylation

0.127347781

2

212

K05575, K05580

ko03013

RNA transport

0.119402985

1

134

K03257

ko02020

Two-component system

0.11066639

2

377

K02040, K08350

ko01055

Biosynthesis of vancomycin group antibiotics

0.108792363

1

29

K01710

ko00523

Polyketide sugar unit biosynthesis

0.098593079

1

32

K01710

ko00330

Arginine and proline metabolism

0.091966665

2

131

K00472, K01572

ko00920

Sulfur metabolism

0.085907839

1

34

K00860

ko00270

Cysteine and methionine metabolism

0.075367382

1

70

K00558

ko03410

Base excision repair

0.06057902

1

41

K02335

ko04110

Cell cycle

0.060121472

1

106

K02604

ko05152

Tuberculosis

0.054554001

1

131

K02040

ko04111

Cell cycle – yeast

0.054007424

1

118

K02604

ko05111

Vibrio cholerae pathogenic cycle

0.048892513

1

43

K03087

ko03020

RNA polymerase

0.043861709

1

51

K03006

ko04115

p53 signaling pathway

0.036197553

1

59

K10808

ko00620

Pyruvate metabolism

0.034831078

1

75

K01572

ko04141

Protein processing in endoplasmic reticulum

0.027176857

1

140

K09503

ko03010

Ribosome

0.026398087

1

144

K02963

ko02010

ABC transporters

0.019687532

1

363

K02040

ko05168

Herpes simplex infection

0.017753549

1

126

K03006

ko05016

Huntington’s disease

0.015013068

1

149

K03006

ko05169

Epstein-Barr virus infection

0.014912981

1

150

K03006