From: Intestinal microbiota of preterm infants differ over time and between hospitals
Hospital 1, week 1 | Hospital 2, week 1 | Hospital 1, week 2 | Hospital 2, week 2 | |||||
---|---|---|---|---|---|---|---|---|
2010 | 2011 | 2010 | 2011 | 2010 | 2011 | 2010 | 2011 | |
n = 9 | n = 13 | n = 12 | n = 17 | n = 11 | n = 13 | n = 15 | n = 21 | |
Birthweight, mean ± sd (g) | 963 ± 216 | 965 ± 261 | 938 ± 234 | 953 ± 223 | 985 ± 193 | 995 ± 261 | 914 ± 216 | 962 ± 207 |
Birth length, mean ± sd (cm) | 35.8 ± 3.0 | 35.2 ± 2.9 | 34.0 ± 3.1 | 34.9 ± 2.9 | 35.8 ± 2.7 | 35.5 ± 2.9 | 33.7 ± 3.5 | 36.3 ± 6.9 |
GA at birth, weeks (25th–75th percentile) | 26 (26–28) | 28 (26–28) | 27 (26.8–28) | 27 (26–28) | 26 (25.5–27.5) | 28 (26–28) | 27 (26–28) | 27 (26–28) |
Male (%) | 5 (56%) | 6 (46%) | 5 (42%) | 7 (41%) | 4 (36%) | 7 (54%) | 6 (40%) | 11 (52%) |
Hispanic (%) | 0 (0%) | 1 (7.7%) | 1 (8.3%) | 0 (0%) | 0 (0%) | 1 (7.7%) | 1 (6.7%) | 0 (0%) |
Black (%) | 5 (56%) | 6 (46%) | 8 (67%) | 6 (35%) | 3 (27%) | 2 (15%) | 10 (67%) | 8 (38%) |
Cesarean section (%) | 5 (56%) | 5 (38%) | 6 (50%) | 10 (59%) | 6 (55%) | 6 (46%) | 7 (47%) | 10 (48%) |
Maternal abx at delivery (%) | 6 (67%) | 10 (77%) | 11 (92%) | 17 (100%) | 8 (73%) | 10 (77%) | 14 (93%) | 20 (95%) |
Maternal age ± sd (years)a | 27.4 ± 1.6 | 28.0 ± 1.4 | 22.5 ± 4.9 | x27.8 ± 6.1 | 28.5 ± 6.7 | 29.1 ± 5.6 | 21.9 ± 5.1 | 27.7 ± 5.7 |
Maternal parity (25th–75th percentile) | 2 (1–3) | 1 (1–3) | 2 (1–3) | 2 (1–2) | 2 (1.5–3) | 1 (1–3) | 2 (1–3) | 1 (1–3) |
Preeclampsia (%) | 1 (11%) | 2 (15%) | 3 (25%) | 1 (5.8%) | 1 (9.1%) | 3 (2.3%) | 3 (20%) | 1 (4.8%) |
Day of life of sample collection, median (25th–75th percentile)b | 7 (5–7) | 6 (5–8) | 6 (5.8–6.3) | 8 (7–8) | 13 (13–14) | 14 (11–14) | 11 (10–12) | 10 (10–12) |
Days on abx in the first 7 days ± sd | 4.0 ± 2.6 | 3.1 ± 2.1 | 4.7 ± 2.0 | 3.8 ± 1.7 | NA | NA | NA | NA |
Days on abx in the first 14 days ± sd | NA | NA | NA | NA | 4.4 ± 3.1 | 3.6 ± 3.8 | 7.6 ± 4.4 | 5.4 ± 3.4 |
Days of life of first enteral feed, mean ± sd | 4.6 ± 3.7 | 2.5 ± 0.66 | 3 ± 1.3 | 2.8 ± 1.2 | 3.6 ± 1.5 | 2.7 ± 0.75 | 3.6 ± 2.4 | 3 ± 1.6 |
Median percent formula feeds in the first 7 days (25th–75th percentile) | 0% (0%, 0%) | 0% (0%, 0%) | 0% (0%, 35.7%) | 0% (0%, 25%) | NA | NA | NA | NA |
Median percent formula feeds in the first 14 days (25th–75th percentile) | NA | NA | NA | NA | 0% (0%, 0%) | 0% (0%, 0%) | 8.3% (0%, 31.7%) | 6.7% (0%, 18.2%) |