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Table 1 Univariable logistic regression of predictors of bacterial identification

From: Cell-associated bacteria in the human lung microbiome

 

Predictors

Outcome: bacteria identified in acellular BAL via pyrosequencing

p value

Odds ratio

BAL features

Bacterial (16S) DNA (log)

0.004

26.93 (4.58–476.29)

% Neutrophils

0.027

1.06 (1.02–1.14)

% Lymphocytes

0.318

0.97 (0.91 1.02)

Antibiotics

Antibiotics (prior 30 days)

0.091

3.00 (0.86 11.29)

Antibiotics (prior 7 days)

0.111

2.76 (0.81 10.14)

Antibiotics (at time of BAL)

0.425

1.67 (0.48 6.10)

Diversity

Shannon Index

0.009

0.31 (0.11–0.67)

Phylum (% relative abundance)

Bacteroidetes

0.349

0.99 (0.95 1.02)

Proteobacteria

0.933

1.00 (0.98 1.02)

Firmicutes

0.601

1.01 (0.98 1.03)

Family (% relative abundance)

Enterobacteriaceae

0.034

0.93 (0.86–0.99)

Prevotellaceae

0.494

0.99 (0.96 1.02)

Pseudomonadaceae

0.367

1.01 (0.99 1.03)

Staphylococcaceae

0.450

1.08 (0.99 1.39)

Streptococcaceae

0.307

0.98 (0.93 1.02)

Veillonellaceae

0.933

1.00 (0.91 1.09)

OTU (% relative abundance)

OTU 0969 (P. fluorescens)

0.194

0.97 (0.94 1.01)

OTU 1053 (P. aeruginosa)

0.168

1.04 (1.00 1.19)

OTU 1054 (Bordetella)

0.932

1.00 (0.94 1.06)

OTU 1072 (Streptococcus)

0.172

0.96 (0.90 1.01)

OTU 1077 (Veillonella)

0.999

1.00 (0.92 1.09)

OTU 1087 (Escherichia)

0.035

0.93 (0.87–0.99)

OTU 1095 (Prevotella)

0.625

0.99 (0.96 1.02)

OTU 1098 (Staphylococcus)

0.442

1.07 (0.99 1.34)

  1. Italicized results: p < 0.05.