Predictors | Outcome: bacteria identified in acellular BAL via pyrosequencing | ||
---|---|---|---|
p value | Odds ratio | ||
BAL features | Bacterial (16S) DNA (log) | 0.004 | 26.93 (4.58–476.29) |
% Neutrophils | 0.027 | 1.06 (1.02–1.14) | |
% Lymphocytes | 0.318 | 0.97 (0.91– 1.02) | |
Antibiotics | Antibiotics (prior 30 days) | 0.091 | 3.00 (0.86– 11.29) |
Antibiotics (prior 7 days) | 0.111 | 2.76 (0.81– 10.14) | |
Antibiotics (at time of BAL) | 0.425 | 1.67 (0.48– 6.10) | |
Diversity | Shannon Index | 0.009 | 0.31 (0.11–0.67) |
Phylum (% relative abundance) | Bacteroidetes | 0.349 | 0.99 (0.95– 1.02) |
Proteobacteria | 0.933 | 1.00 (0.98– 1.02) | |
Firmicutes | 0.601 | 1.01 (0.98– 1.03) | |
Family (% relative abundance) | Enterobacteriaceae | 0.034 | 0.93 (0.86–0.99) |
Prevotellaceae | 0.494 | 0.99 (0.96– 1.02) | |
Pseudomonadaceae | 0.367 | 1.01 (0.99– 1.03) | |
Staphylococcaceae | 0.450 | 1.08 (0.99– 1.39) | |
Streptococcaceae | 0.307 | 0.98 (0.93– 1.02) | |
Veillonellaceae | 0.933 | 1.00 (0.91– 1.09) | |
OTU (% relative abundance) | OTU 0969 (P. fluorescens) | 0.194 | 0.97 (0.94– 1.01) |
OTU 1053 (P. aeruginosa) | 0.168 | 1.04 (1.00– 1.19) | |
OTU 1054 (Bordetella) | 0.932 | 1.00 (0.94– 1.06) | |
OTU 1072 (Streptococcus) | 0.172 | 0.96 (0.90– 1.01) | |
OTU 1077 (Veillonella) | 0.999 | 1.00 (0.92– 1.09) | |
OTU 1087 (Escherichia) | 0.035 | 0.93 (0.87–0.99) | |
OTU 1095 (Prevotella) | 0.625 | 0.99 (0.96– 1.02) | |
OTU 1098 (Staphylococcus) | 0.442 | 1.07 (0.99– 1.34) |