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Table 1 Comparison of ALDEx and ALDEx2

From: Unifying the analysis of high-throughput sequencing datasets: characterizing RNA-seq, 16S rRNA gene sequencing and selective growth experiments by compositional data analysis

Property

ALDEx

ALDEx2

Significance tests

Effect size and ad hoc

Welch’s t or Wilcoxon

Multiple test

No

Benjamini–Hochberg

correction

  

Minimum dataset

Two samples per

Three samples per

 

group

group

Maximum dataset

3×3×5, 000

>300×300×20, 000

 

2×2×20, 000

 
  1. Dataset: samples in A × samples in B × number of features.
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Microbiome

ISSN: 2049-2618

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