Figure 1

Changes in microbiota diversity and composition following fecal transplantation in CDI patients. Microbiota communities were profiled from three CDI patients, healthy donor, and from each patient over a 4-month period following fecal transplantation. Samples were collected periodically as shown in (A). Community diversity and evenness were assessed by calculating the Shannon H’ (diversity, B) and Simpson E (evenness, C) indices based on microarray phylotype abundance data. Community structure in each sample is shown at class level in (D) (distribution is based on microarray data) and (E) (distribution is based on sequencing data). Missing data represent samples that had lower amount of fecal material available; thus not all analyses could be carried out for these samples.