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Table 1 Univariate association of major taxa with psoriasis status using Kruskal-Wallis ANOVA

From: Community differentiation of the cutaneous microbiota in psoriasis

Taxonomic level

Taxon

Kruskal-Wallis χ2

df

Median abundance

FDR adjusted P valuea

Control

Unaffected

Lesion

Phylum

Bacteria;Acidobacteria

18.68

2

0.97%*

0.48%**

0.18%***

6.14E-04

Bacteria;Deinococcus-Thermus

9.14

2

0.37%*

0.22%**

0.14%***

2.41E-02

Bacteria;Otherb

14.27

2

2.52%*

2.20%**

1.42%***

2.79E-03

Bacteria;Proteobacteria

7.42

2

33.32%**

36.21%*

30.75%***

4.27E-02

Class

Acidobacteria;Acidobacteria_Gp4

14.08

2

0.92%*

0.41%**

0.12%***

4.39E-03

Bacteroidetes;Sphingobacteria

8.53

2

1.70%*

1.50%**

0.74%***

3.52E-02

Deinococcus-Thermus;Deinococci

9.14

2

0.37%*

0.22%**

0.14%***

3.44E-02

Proteobacteria;Alphaproteobacteria

7.63

2

16.44%*

11.37%**

7.64%***

4.41E-02

Order

Acidobacteria_Gp4;Gp4

14.08

2

0.92%*

0.41%**

0.12%***

5.70E-03

Sphingobacteria;Sphingobacteriales

8.53

2

1.70%*

1.50%**

0.74%***

3.05E-02

Alphaproteobacteria;Rhizobiales

11.53

2

13.63%*

7.94%**

4.11%***

1.36E-02

Betaproteobacteria;Burkholderiales

8.80

2

9.33%**

11.61%*

5.95%***

3.05E-02

Gammaproteobacteria;Xanthomonadales

9.34

2

1.83%*

1.23%**

0.32%***

3.05E-02

Family

Gp4;Other

14.08

2

0.92%*

0.41%**

0.12%***

9.22E-03

Sphingobacteriales;Chitinophagaceae

10.61

2

0.93%*

0.56%**

0.34%***

1.74E-02

Bacillales;Bacillaceae

11.75

2

0.61%*

0.31%**

0.09%***

1.18E-02

Rhizobiales;Bradyrhizobiaceae

12.95

2

2.21%*

1.89%**

0.73%***

1.08E-02

Rhizobiales;Methylobacteriaceae

12.07

2

8.43%*

4.42%**

2.39%***

1.18E-02

Burkholderiales;Burkholderiaceae

8.46

2

4.89%*

4.68%**

1.95%***

3.82E-02

Burkholderiales;Comamonadaceae

7.71

2

2.05%*

1.64%**

0.94%***

4.94E-02

Xanthomonadales;Xanthomonadaceae

9.61

2

1.79%*

1.23%**

0.31%***

2.45E-02

Genus

Gp4;Other

14.08

2

0.92%*

0.41%**

0.12%***

2.98E-03

Chitinophagaceae;Flavisolibacter

14.32

2

0.22%*

0.05%**

0.02%***

2.98E-03

Bacillaceae;Geobacillus

8.03

2

0.06%*

0.00%***

0.00%***

3.83E-02

Methylobacteriaceae;Methylobacterium

12.19

2

8.43%*

4.42%**

2.39%***

5.48E-03

Burkholderiaceae;Cupriavidus

21.50

2

3.20%**

3.38%*

0.73%***

1.83E-04

Comamonadaceae;Schlegelella

25.21

2

0.64%*

0.35%**

0.05%***

5.71E-05

Xanthomonadaceae;Other

12.74

2

1.46%*

0.39%**

0.17%***

4.85E-03

Operational taxonomical unit (OTU)

Methylobacterium;484

15.16

2

5.51%*

2.65%**

1.22%***

1.66E-03

Gp4;3855

16.95

2

0.72%*

0.06%**

0.00%***

9.04E-04

Xanthomonadaceae;6162

10.04

2

1.06%*

0.16%**

0.02%***

1.72E-02

Cupriavidus;6869

20.96

2

2.38%**

2.40%*

0.55%***

1.83E-04

Schlegelella;13613

26.57

2

0.47%*

0.22%**

0.00%***

2.21E-05

 

Methylobacterium;24283

9.11

2

1.02%*

0.74%**

0.34%***

2.28E-02

  1. Coding indicates high (*), intermediate (**), or low (***) abundance values in each row.
  2. aOnly taxa significant at 5% FDR are shown.
  3. bThis taxon represents all sequences that were not assigned to a known phylum. It is significant at all taxonomic levels.
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