Figure 5

Principal coordinates analysis (PCoA) of weighted Unifrac distances. Based on separation of the relative values of the percentage variability explained by the principal axes, we chose to represent the cutaneous microbiome of our study in the first two components (A). (B) On the scatterplot of the first two principal axes of the PCoA, each point represents an individual subject (red = control, green = unaffected, blue = lesion) and the colored boxes are positioned at the geometrical center of all the points in the corresponding groups. The distributions of the points along PC1 (C) and PC2 (D) are shown in the boxes (representing the middle 50% of the data) and whiskers (95% interval) plots. Along PC1, lesion samples are significantly different from control (P <0.001) and unaffected (P <0.015) based on one-way analysis of variance (ANOVA) with Tukey honestly significant difference (HSD) multiple comparison correction.