Figure 3

Intestinal community clustering of Clostridium difficile infection (CDI) cases and control subjects based on principal coordinate analysis (PCoA). Results are presented for (A) V1-V3 and (B) V3-V5 sequence sets. Case patients (n = 25) are colored in red and control patients (n = 25) are colored in blue. Patients with the lowest degree of intestinal biodiversity (n = 6; all of these patients are cases) are shown with open circles. The percentage of variation explained by each principal coordinate (PC) is indicated on the corresponding axis.