Treatment | Fold change ± SD | ||
---|---|---|---|
 | H. hepaticus infected | Total bacterial load | H. hepaticus load |
Cefoperazone (cef) treatment | Â | Â | Â |
Control 1 (no cef) | No | calibrator | N/A |
Control 2 (1 day recovery from cef) | No | -3,333.00 ± 0.34 | N/A |
Control 3 (6 wk recovery from cef) | No | 2.16 ± 1.18 | N/A |
Community 1 (no cef) | Yes | 1.25 ± 0.75 | calibrator |
Community 2 (1 day recovery from cef before infection) | Yes | 4.48 ± 2.55 | -1.12 ± 2.79 |
Community 3 (6 wk recovery from cef before infection) | Yes | -1.35 ± 0.71 | 3.94 ± 6.30 |
Vancomycin (vanc) treatment | Â | Â | Â |
Control 4 (no vanc) | No | 1.17 ± 0.68 | N/A |
Control 5 (vanc) | No | 1.95 ± 1.41 | N/A |
Control 6 (vanc + 11 days recovery) | No | 1.41 ± 0.91 | N/A |
Community 4 (no vanc) | Yes | 1.90 ± 1.91 | 1.04 ± 0.30 |
Community 5 (vanc) | Yes | 1.98 ± 1.62 | -1.59 ± 0.52 |
Community 6 (vanc + 11 days recovery) | Yes | 1.14 ± 1.16 | 1.28 ± 0.56 |
Germfree mice infected with H. hepaticus | N/A | -2.94 ± 1.90 |