Skip to main content
Figure 2 | Microbiome

Figure 2

From: The effects of intestinal microbial community structure on disease manifestation in IL-10-/- mice infected with Helicobacter hepaticus

Figure 2

H. hepaticus triggered inflammation in conventionally raised IL10-/-C57BL/6 mice compared to germfree counterparts. Representative histologic sections of mouse cecum are depicted. (A) H. hepaticus- uninfected conventionally raised mice appear normal. (B) H. hepaticus-infected conventional section shows edema, hyperplasia and inflammatory infiltrate. (C) H. hepaticus- uninfected germfree control, and (D) H. hepaticus- infected germfree cecum sections are both normal, with few signs of inflammation. (E) Quantification of indicators of pathology showing significant inflammation only in histologic sections from H. hepaticus- infected conventionally raised mice. *Statistically significant changes (P <0.05).

Back to article page

Microbiome

ISSN: 2049-2618

Contact us