Fig. 3

Evolution of viruses related to human and domestic animal pathogens. a Maximum likelihood phylogenetic trees of viruses harboring replication-associated proteins. All the trees are midpoint rooted, with the scale bar representing the count of amino acid substitutions per site. The name of the viral group is shown above each phylogeny. For each tree, bootstrap values are marked on the branch node. The virus names included the viral species, strain name, host species, and sampling country. The viruses identified in the present study are indicated in red. b Sequence alignment of the spike protein in hibecoviruses, with the furin cleavage site highlighted in red boxes. c Genomic similarity among related orthorubulaviruses with human orthorubulavirus 2 (parainfluenza 2) as a query