Fig. 3

Visualization Results of Blood Transcriptomic Sequencing and Analysis. A-C, the volcano plots of the significantly up-regulated (orange) and down-regulated (green) genes between the AMW and Control groups on days -3 (A), 30 (B), and 60 (C). D-F, the bubble plots of the top 20 enriched KEGG pathways from the differentially expressed genes (DEGs) between the AMW and Control groups on days -3 (A), 30 (B), and 60 (C). In D-F, “Count” indicates the number of DEGs which were annotated to the corresponding pathway: a bigger value indicates more DEGs were enriched in this pathway; “Gene Ratio” indicates the ratio of the number of DEGs which was annotated to the corresponding pathways to the total number of DEGs: a bigger value indicates a higher enrichment level of DE Metas in this pathway; and “Adjusted p-values” indicates the significance corrected through multiple hypotheses. The color of symbols indicates their corresponding adjusted p-value: a bigger value indicates greater inspection reliability