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Fig. 6 | Microbiome

Fig. 6

From: Divergent maturational patterns of the infant bacterial and fungal gut microbiome in the first year of life are associated with inter-kingdom community dynamics and infant nutrition

Fig. 6

Atypical bacterial and fungal alpha diversity trends are associated with functional differences reflected in urine metabolites at 3 months. Normalized concentrations of A trimethylamine N-oxide (TMAO), B indole acetic acid (IAA), C creatine, and D 2-furoylglycine by bacterial alpha diversity trend (increase: n = 74, decrease: n = 24) and E lactic acid by fungal alpha diversity trend (decrease: n = 73, increase: n = 18) at 3 months observed in urine, assessed by t-test. Metabolite concentrations were normalized using the median, log-transformed, and pareto-scaled (mean-centered and divided by the square root of the standard deviation of each metabolite) and a false discovery rate (FDR) cutoff of 0.1 was applied. No significant differences in urine metabolite concentrations were observed at 12 months

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Microbiome

ISSN: 2049-2618

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