Fig. 5
From: Gut microbiota-derived LCA mediates the protective effect of PEDV infection in piglets
Efects of Lactobacillus reuteri and Lactobacillus amylovorus on PEDV infection in piglets. Lactobacillus reuteri and Lactobacillus amylovorus alleviate PEDV infection. A Protective model of Lactobacillus reuteri and Lactobacillus amylovorus in piglets (Am, Min pigs gavaged with Lactobacillus amylovorus; Re, Min pigs gavaged with Lactobacillus reuteri; Am/Re, Min pigs gavaged with Lactobacillus amylovorus and Lactobacillus reuteri; PBS, Min pigs gavaged with PBS; NC, normal control group). Comparative analysis of survival (B), weight loss (C), and diarrhea (D) in each group of piglets. E Analysis of average fluorescence intensity. F Comparison of histopathological changes (H&E staining) and PEDV viral load in the jejunum of piglets on day 8 post-infection. The left image is scanned at a magnification of 40×, and the right image is scanned at a magnification of 200×. G Histopathological scoring of tissues. The results are presented as the means ± SD, and statistical significance was calculated by one-way ANOVA. *P < 0.05; **P < 0.01; ****P < 0.0001