Fig. 7

The abundances of age-associated CAZy families and their predicted bacterial families. A Heatmap depicting the age-associated CAZy enzymes. The color of cells from purple to red corresponds to the relative abundance of ARGs on a log scale from low to high. GH24 included lysozyme (EC 3.2.1.17) which is the major enzyme in colostrum. GH5 and GH6 contained cellulase (EC 3.2.1.4) and cellobiohydrolase (EC 3.2.1.91), GH5 included β-glucosidase (EC 3.2.1.21), and GH57 had α-amylase (EC 3.2.1.1). B The most abundant host bacterial families predicted to produce the CAZy are shown in the heatmap. The predicted bacteria, including Pasteurellaceae, Enterobacteriaceae, and Clostridiaceae, were abundant on d1, matching the abundances of the ARGs bacterial origins. The contributions of Prevotellaceae, Fibrobacteraceae, and Xanthomonadaceae to CAZy enzymes were high in later days, likely resulting from the increased intake of the solid diet