Table 1 Summary of in vitro effects of loperamide on zebrafish strains. Significant changes in growth in media, survival in water, and in vivo zebrafish colonization for loperamide treated, compared to DMSO control
From: Anti-diarrheal drug loperamide induces dysbiosis in zebrafish microbiota via bacterial inhibition
Strain | Growth in media | Survival in water | Zebrafish mono-colonization |
|---|---|---|---|
S1. Pseudomonas mosselii | Promoted | No effect | Reduced at T0 and T1, and then recovery |
S2. Variovorax gossypii | No effect | Increased from 6 h | No detected effect |
S3. Pseudomonas nitroreducens | No effect | Increased from 24 h | No detected effect |
S4. Achromobacter marplatensis | Reduced | No effect | No detected effect |
S5. Stenotrophomonas maltophilia | Reduced | No effect | No detected effect |
S6. Aeromonas caviae | Inhibited | No effect | No detected effect |
S7. Aeromonas veronii | Inhibited | Decreased at 24 h | Reduced at T0 and T5 |
S8. Rhizobium sp. | Inhibited | Increased from 24 h | Increased at T5 |
S9. Ochrobactrum tritici | Inhibited | No effect | Reduced at T0 |
S10. Flavobacterium johnsoniae | Inhibited | No effect | Reduced at T0 and T1, and then recovery |