Fig. 5
From: Anti-diarrheal drug loperamide induces dysbiosis in zebrafish microbiota via bacterial inhibition
Loperamide affects mix5-colonized gnotobiotic zebrafish bacterial load and composition. A Total CFUs per fish of mix5-colonized fish after exposure to loperamide at 3 timepoints (n = 3–4 fish). Each point represents a single zebrafish (mean of 3 technical replicates). No significant changes were found for loperamide treatment, compared to DMSO. Wilcoxon test. Note log scale for CFUs. B Percent abundance of each strain per mix5-colonized fish. Each bar is an individual fish sample. C Percent abundance of each strain in mix5-colonized fish per timepoint and treatment. Each point represents a single zebrafish (mean of 3 technical replicates). *p < 0.05 for loperamide treatment, compared to DMSO. Wilcoxon test