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Fig. 10 | Microbiome

Fig. 10

From: MGS2AMR: a gene-centric mining of metagenomic sequencing data for pathogens and their antimicrobial resistance profile

Fig. 10

Example of the MGS2AMR Explorer visualization. A A heatmap of detected ARG and annotated bacteria, colored by the min–max normalized score (1 represents the top score, 0—no association determined). B Detailed exploration of specific bacteria and associated ARG. The blue-colored lines denote the genus in focus, with gray lines representing other top-scoring bacteria that match a particular ARG. Lighter blue shades are non-top-scoring matches. The image shows the alternative views of the same report upon changing the focus across the determined genera. Top: Acinetobacter is likely to be present as all ARG are top scoring with only two (blaOXA and sul2) having a potential association with another bacterium. Middle: Klebsiella is probably not present in the sample as all ARG are also present in Acinetobacter, and only 1 ARG (sul2) shares a top score (i.e., scores for all other ARG are lower than those for Acinetobacter). Bottom: Bacteroides has 6 top-scoring ARG that are not contested, so it likely is present in the sample

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