Fig. 2

Dysregulated AHR/NF-κB signaling mediates ASD susceptibility in PCE-induced IUGR rats. A, B, K, L Protein levels of AHR and P-NF-κB. C, M mRNA level of Ahr. D Schematic of the experimental design in vivo. E, F An illustrative example of travel pathways of rats in social choice test, open field test, and Y maze test. G Time of rats spent in each zone in social choice test. H Marble burying index in marble burying test. I Time spent in the center, distance traveled in the center, and total distance traveled in open field test. J Spontaneous alteration rate in Y maze test. Dots in panels represent individual samples. Data are presented as mean ± SEM. ^*P < 0.05, ^**P < 0.01, and ^***P < 0.001