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Table 1 Overview of participant characteristics

From: Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

Variable category

Low inflammation (n=6)

Medium inflammation (n=25)

High Inflammation (n=12)

p value

Ethnicity (Caucasian) no., %

5 (83%)

22 (88%)

9 (75%)

0.598^

Age (median ± SD; range)

25 ± 11.2 (19–46)

37 ± 12.1 (21–64)

42.5 ± 24.04 (23–88)

0.171χ

Vaginal pH (median ± SD; range)

4.25 ± 0.24 (4.0–4.7)

4.7 ± 0.44 (4.0–5.5)

4.8 ± 0.46 (4.0–5.8)

0.034χ

BV+ (Amsel criteria), no., %

0 (0%)

4 (16%)

4 (33%)

0.248^

Vaginal symptoms in the past month, any (no., %)a

4 (67%)

9 (36%)

3 (25%)

0.222^

Ectopy (no., %)

0 (0%)

7 (28%)

3 (25%)

0.473^

Any intercourse past 30 days

4 (67%)

15 (60%)

4 (42%)

0.631^

Condom use (no., %)

0 (0%)

6 (24%)

3 (25%)

0.598^

Any birth control use

1 (17%)

Oral—1

10 (40%)

Oral—2

Ring—2

IUD—6

2 (17%)

Oral—1

IUD—1

0.328^

Any STI, ever (no., %)

0 (0%)

10 (40%)

2 (17%)

0.117^

Lactobacillus dominant microbiome

6 (100%)

16 (64%)

7 (58%)

0.184^

  1. ^p value calculated using Monte Carlo to stimulate p value with Fisher’s exact test, based on 2000 iterations
  2. χp value calculated using the Kruskal-Wallis test
  3. aSelf-reported vaginal symptoms including pain, discomfort, itchiness, discharge, bleeding