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Fig. 6 | Microbiome

Fig. 6

From: Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

Fig. 6

Bayesian network analysis of cervicovaginal inflammation. Major features are colored by dataset. Node size is representative of the number of edges per node, with larger nodes having more edges (A). Heatmap of the top five features selected by Random Forest based on Gini importance from host proteome, microbiome, bacterial protein, and metabolome datasets (B). Each feature was assigned to above or below median level and used for unsupervised hierarchical clustering. Inflammation status and levels of APCs are overlaid. Samples significantly cluster by inflammation status (chi-square p=5.34 × 10−5). Pie charts show the distribution of bacterial taxa for each protein included in the heatmap

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Microbiome

ISSN: 2049-2618

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