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Fig. 5 | Microbiome

Fig. 5

From: Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

Fig. 5

Cervicovaginal metabolome differences between women with high and low inflammation. A Hierarchical clustering of differentially abundant (p<0.05) metabolites based on inflammation group. B Log2 normalized abundance of xanthine identified in CVL samples by inflammation group with median indicated. C Log2 normalized abundance of lactate identified in CVL samples by inflammation group with median indicated. Adjusted p values are reported and were calculated using the Kruskal-Wallis test with Dunn’s correction for multiple comparisons. Two participants from the high inflammation group did not have samples available for metabolomics analysis. N=41

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