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Fig. 4 | Microbiome

Fig. 4

From: Increased genital mucosal cytokines in Canadian women associate with higher antigen-presenting cells, inflammatory metabolites, epithelial barrier disruption, and the depletion of L. crispatus

Fig. 4

Cervicovaginal microbiome composition and functional differences between women with high and low genital inflammation. Proportion plots of A taxa and B ko-level bacterial functions identified in cervicovaginal lavage by mass spectrometry. Participants are grouped by inflammation status. Two participants in the medium inflammation group did not have bacterial functions mapped to the identified bacterial proteins. C Microbial proportion of L. crispatus grouped by inflammation status with median identified. D Proportion of ko-level bacterial functions by inflammation status. Pie charts show the distribution of bacterial taxa for each function. E Bacterial proteins that differed by inflammation status. Pie charts show the distribution of bacterial taxa for each protein. Adjusted p values are reported and were calculated using the Kruskal-Wallis test with Dunn’s correction for multiple comparisons. N=43

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