Fig. 1From: Picodroplet partitioned whole genome amplification of low biomass samples preserves genomic diversity for metagenomic analysisIllustration of the method. a DNA is denatured with alkaline solution and neutralized, and the MDA reaction mix is prepared. Aliquots of these solutions are mixed either directly for a bulk reaction in a PCR tube or in a microfluidic chip b to generate an emulsion with c homogeneous picoliter-sized droplets. The generated emulsion is collected in a PCR tube plugged by a PDMS plug to allow maintained droplet stability during long-term incubationBack to article page